Abstract
In proton magnetic resonance studies of polypeptides in solution, the spectral behaviour of the α-CH proton peak depends on the nature of the solvent system, the side chain and the molecular weight. It is considered a more straightforward indicator of conformation than the amide NH peak.
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References
Ferretti, J. A., Chem. Commun., 1030 (1967).
Bradbury, E. M., and Rattle, H. W. E., Polymer (in the press).
Stewart, W. E., Mandelkern, L., and Glick, R. E., Biochemistry, 6, 143 (1967).
Markley, J. L., Meadows, D. H., Jardetzky, O., J. Mol. Biol., 27, 25 (1967).
Jardetzky, O., in First Biopolymers Symp., 501 (Interscience Publishers, 1964).
Goodman, M., and Masuda, Y., Biopolymers, 2, 107 (1964).
Bradbury, E. M., Crane-Robinson, C., and Rattle, H. W. E., in Symp. Mag. Reson. Tech. Biol. Systems, Tokyo (1967).
Bradbury, E. M., Crane-Robinson, C., Goldman, H., Rattle, H. W. E., and Stephens, R. M., J. Mol. Biol., 29, 507 (1967).
Bradbury, E. M., Crane-Robinson, C., Rattle, H. W. E., and Stephens, R. M., Conformations of Biopolymers, edit. by Ramachandran (Academic Press, 1967).
Maryborough, D. I., Orrell, K. G., and Rydon, H. N., Chem. Commun., 518 (1965).
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BRADBURY, E., CRANE-ROBINSON, C. & RATTLE, H. Proton Magnetic Resonance Studies of the Helix–Coil Transition in Polypeptides. Nature 216, 862–864 (1967). https://doi.org/10.1038/216862a0
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DOI: https://doi.org/10.1038/216862a0
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