Abstract
The biosynthesis of glycerides from glycerolphosphate and palmitate, catalysed by mitochondrial and microsomal fractions, is greatly stimulated by the supernatant fraction (6,000,000×g-min). This is caused by the presence of a specific phosphatidate phosphohydrolase, unsaturated long-chain fatty acids and unspecific protein(s) in the supernatant fraction.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kornberg, A., and Pricer, W. E., J. Biol. Chem., 204, 329 (1953).
Kornberg, A., and Pricer, W. E., J. Biol. Chem., 204, 345 (1953).
Senior, J. R., and Isselbacher, K. J., Biochim. Biophys. Acta, 44, 399 (1960).
Hokin, L. E., and Hokin, M. R., J. Gen. Physiol., 44, 51 (1961).
Goldman, P., and Vagelos, P. R., J. Biol. Chem., 236, 2620 (1961).
Coleman, R., and Hübscher, G., Biochim. Biophys. Acta, 56, 479 (1962).
Johnston, J. M., and Bearden, J. H., Biochim. Biophys. Acta, 56, 365 (1962).
Senior, J. R., and Isselbacher, K. J., J. Biol. Chem., 237, 1454 (1962).
Ailhaud, G., Samuel, D., and Desnuelle, P., Biochim. Biophys. Acta, 67, 150 (1963).
Hübscher, G., Clark, B., Webb, M. E., and Sherratt, H. S. A., in Biochemical Problems of Lipids (edit. by Fraser, A. C.), 201 (Elsevier, Amsterdam, 1963).
Wilgram, G. F., and Kennedy, E. P., J. Biol. Chem., 238, 2615 (1963).
Brown, J. L., and Johnston, J. M., Biochim. Biophys. Acta, 84, 264 (1964).
Korchak, H. M., and Masoro, E. J., Biochim. Biophys. Acta, 84, 750 (1964).
Pynadath, T. I., and Kumar, S., Biochim. Biophys. Acta, 84, 251 (1964).
Brindley, D. N., and Hübscher, G., Biochim. Biophys. Acta, 106, 495 (1965).
Sedgwick, B., and Hübscher, G., Biochim. Biophys. Acta, 106, 63 (1965).
Stein, Y., and Shapiro, B., Biochim. Biophys. Acta, 24, 197 (1957).
Stein, Y., Tietz, A., and Shapiro, B., Biochim. Biophys. Acta, 26, 286 (1957).
Hübscher, G., Smith, M. E., and Gurr, M. I., in Metabolism and Pnysiological Function of Lipids (edit. by Dawson, M. R. C., and Rhodes, D. N.), 299 (John Wiley, London, 1964).
Smith, M. E., and Hübscher, G., Biochem. J., 101, 306 (1966).
Dils, R., and Clark, B., Biochem. J., 84, 19 (1962).
Roncari, D. A. K., and Hollenberg, C. H., Biochim. Biophys. Acta, 137, 446 (1967).
Johnston, J. M., Rao, G. A., Lowe, P. A., and Schwarz, B. E., Lipids, 2, 14 (1967).
Brindley, D. N., Smith, M. E., Sedgwick, B., and Hübscher, G., Biochim. Biophys. Acta, 144, 285 (1967).
Lands, W. E. M., and Hart, P., J. Lipid Res., 5, 81 (1964).
Brindley, D. N., and Hübscher, G., Biochim. Biophys. Acta, 125, 92 (1966).
Young, R. J., and Garrett, R. L., J. Nutrit., 81, 321 (1963).
Tzur, R., and Shapiro, B., J. Lipid Res., 5, 542 (1964).
Lands, W. E. M., and Hart, P., J. Biol. Chem., 240, 1905 (1965).
Smith, S. W., Weiss, S. B., and Kennedy, E. P., J. Biol. Chem., 228, 915 (1957).
Smith, M. E., Sedgwick, B., Brindley, D. N., and Hübscher, G., Europ. J. Biochem. (in the press).
Sedgwick, B., and Hübscher, G., Biochim. Biophys. Acta, 144, 397 (1967).
Farstad, M., Bremer, J., and Norum, K. R., Biochim. Biophys. Acta, 132, 492 (1967).
Farstad, M., Abstracts Fourth Meeting FEBS, Oslo, 55 (1967).
Krebs, E. G., Love, D. S., Bratvold, G. E., Trayser, K. A., Meyer, W. L., and Fischer, E. D., Biochemistry, 3, 1022 (1964).
Bar-Tana, J., and Shapiro, B., Biochem. J., 93, 533 (1964).
Ailhaud, G. P., and Vagelos, P. R., J. Biol. Chem., 241, 3866 (1966).
Goldfine, H., J. Biol. Chem., 241, 3864 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HÜBSCHER, G., BRINDLEY, D., SMITH, M. et al. Stimulation of Biosynthesis of Glyceride. Nature 216, 449–453 (1967). https://doi.org/10.1038/216449a0
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1038/216449a0
This article is cited by
-
Relationship between lipid composition and drug metabolizing capacity of human liver
European Journal of Clinical Pharmacology (1985)
-
Fatty acid specificity of glyceride synthesis by homogenates of bovine mammary tissue
Lipids (1971)
-
Characteristics of fatty acid esterification by homogenates of bovine mammary tissue
Lipids (1971)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.