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Cytopathic Effects of the Parainfluenza Virus SV5 in Vero Cells

Abstract

SIMIAN virus 5 (S V5) (ref. 1), a member of the parainfluenza-mumps-Newcastle disease subgroup of myxoviruses2, is a common contaminant of primary cultures of monkey kidney cells. S V5 virus multiplies to high titre in monkey kidney cells, but causes only minimal cytopathic effects3. Haemadsorption is necessary to show the presence of the virus4. In contrast, in BHK-21 cells, it produces extensive fusion and disintegration, yielding relatively little virus5.

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RHIM, J., SCHELL, K. Cytopathic Effects of the Parainfluenza Virus SV5 in Vero Cells. Nature 216, 271–272 (1967). https://doi.org/10.1038/216271a0

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  • DOI: https://doi.org/10.1038/216271a0

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