Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Specific Binding of Sodium and Potassium Ions in Erythrocyte Membranes

Abstract

In erythrocytes, the binding of sodium and potassium ions to sites in the membrane is specific and the number of sites is extremely small. Addition of ATP to the medium increases the binding of sodium ions by 50 per cent or more and it is suggested that ion binding is connected with the ion pump.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Skou, J. C., Prog. in Biophys., 14, 131 (1964).

    Article  CAS  Google Scholar 

  2. Skou, J. C., Physiol. Rev., 45, 596 (1965).

    Article  CAS  Google Scholar 

  3. Whittam, R., Transport and Diffusion in Red Blood Cells (Edward Arnold, London, 1964).

  4. Glynn, I. M., J. Physiol., 160, 18 (1962).

    Google Scholar 

  5. Katchalsky, A., Ginzburg, B. Z., and Ginzburg, M., First Intern. Symp. on Water Desalination, Washington, DC, 1, 441 (1965).

    Google Scholar 

  6. Blumental, R., Ginzburg, B. Z., and Katchalsky, A., Proc. First Intern. Conf. on Haematol. (edit. by Copley, A. L.), 91 (Pergamon Press, 1967).

    Google Scholar 

  7. Shaw, T. I., thesis, Univ. Cambridge (1954).

  8. Glynn, I. M., Prog. in Biophys., 8, 241 (1957).

    CAS  Google Scholar 

  9. Cohen, D., J. Gen. Physiol., 45, 959 (1962).

    Article  CAS  Google Scholar 

  10. Glynn, I. M., J. Physiol., 136, 148 (1952).

    Article  Google Scholar 

  11. Solomon, A. K., Gill, T. J., and Gold, L., J. Gen. Physiol., 40, 327 (1956).

    Article  CAS  Google Scholar 

  12. Dunham, E. T., and Glynn, I. M., J. Physiol., 156, 273 (1961).

    Article  Google Scholar 

  13. Post, R. L., Merritt, C. R., Kinsolving, C. R., and Albright, C. D., J. Biol. Chem., 235, 1796 (1960).

    CAS  PubMed  Google Scholar 

  14. Skou, J. C., Biochim. Biophys. Acta, 58, 314 (1962).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

GINZBURG, B., FRIEDLANDER, T. & POUCHOVSKY, E. Specific Binding of Sodium and Potassium Ions in Erythrocyte Membranes. Nature 216, 1185–1188 (1967). https://doi.org/10.1038/2161185a0

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2161185a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing