Significance of Mitotic Spindle Fibre Orientation in the Neural Tube


CELLS in the neural tube are usually said to divide with their spindle fibres oriented parallel to the luminal surface1. The plane of cleavage is always at right angles to the direction of the spindle fibres2, and so the cleavage between daughter cells would always be perpendicular to the luminal surface of the neural tube.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Fujita, S., Nature, 185, 702 (1960).

  2. 2

    Mazia, D., Sci. Amer., 93, 2 (1961).

  3. 3

    Hamburger, V., and Hamilton, H. L., J. Morphol., 88, 49 (1951).

  4. 4

    Fujita, H., and Fujita, S., Z. Zellforsch., 60, 463 (1963).

  5. 5

    Herman, L., and Kauffman, S. L., Dev. Biol., 13, 145 (1966).

  6. 6

    Wechsler, W., Z. Zellforsch., 70, 240 (1966).

Download references

Author information



Rights and permissions

Reprints and Permissions

About this article

Cite this article

MARTIN, A. Significance of Mitotic Spindle Fibre Orientation in the Neural Tube. Nature 216, 1133–1134 (1967).

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.