Possible in vivo De-acetylation of N-Acetylhistamine in Man


AUTHENTIC N-acetylhistamine is degraded by human faeces in vitro and a histamine-like activity concurrently evolves1, so the underlying mechanism for the decay seems to be de-acetylation.

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  1. 1

    Sjaastad, O., Scand. J. Gastroent., 1, 173 (1966).

    CAS  Article  Google Scholar 

  2. 2

    Tabor, H., and Mosettig, E., J. Biol. Chem., 180, 703 (1949).

    CAS  PubMed  Google Scholar 

  3. 3

    Anrep, G. V., Ayadi, M. S., Barsoum, G. S., Smith, J. R., and Talaat, M. M., J. Physiol., 103, 155 (1944–45).

    CAS  Article  Google Scholar 

  4. 4

    Dunér, H., and Pernow, B., Scand. J. Clin. Lab. Invest., 8, 296 (1956).

    Article  Google Scholar 

  5. 5

    Sjaastad, O., Scand. J. Clin. Lab. Invest., 18, 617 (1966).

    CAS  Article  Google Scholar 

  6. 6

    Schayer, R. W., Physiol. Rev., 39, 116 (1959).

    CAS  Article  Google Scholar 

  7. 7

    Sjaastad, O., Acta Pharmacol. (Kbh.), 24, 189 (1966).

    CAS  Article  Google Scholar 

  8. 8

    Eiseman, B., Amer. J. Digest. Dis., 7, 1099 (1962).

    Article  Google Scholar 

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SJAASTAD, O. Possible in vivo De-acetylation of N-Acetylhistamine in Man. Nature 216, 1111–1112 (1967). https://doi.org/10.1038/2161111a0

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