“Species Specificity” of Interferons: a Misnomer?


IN 1961, there were two reports of monkey interferon protecting human cells1,2 and one of human interferon protecting monkey cells3, but in none of these was the oxtent of the cross-reaction measured. In view of the usual strict “species specificity” of iiiterferons (for example, chick interferon is not active in mouse cells, human cells4 or duck cells5), it seemed worthwhile to examine the cross-reactivity of human and monkey interferons.

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    Chany, C., Virology, 13, 485 (1961).

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    Merigan, T. C., Science, 145, 811 (1964).

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BUCKNALL, R. “Species Specificity” of Interferons: a Misnomer?. Nature 216, 1022–1023 (1967). https://doi.org/10.1038/2161022a0

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