Abstract
RECENT reports have indicated that antilymphocytic IgG, in addition to inhibiting the homograft reaction, is capable of suppressing the formation of humoral antibody against a number of antigens1–4. Somewhat conflicting results have appeared, however, on the ability of antilymphocytic antibody to suppress the formation of antibody against itself, or against normal IgG globulin obtained from the species in which the antibody was produced5–7. We have investigated this problem by studying the effect of prolonged administration of antilymphocytic IgG (horse anti-rat) on the elimination of normal horse IgG, labelled with iodine-131, from rats.
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CLARK, J., JAMES, K. & WOODRUFF, M. Elimination of Normal Horse IgG labelled with Iodine-131 in Rats receiving Horse Anti-rat Lymphocytic IgG. Nature 215, 869–870 (1967). https://doi.org/10.1038/215869a0
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DOI: https://doi.org/10.1038/215869a0
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