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Induction of Mitotic Recombination in Saccharomyces cerevisiae by Ethyl Methane Sulphonate

Nature volume 215, pages 660–661 (1967)Cite this article

Abstract

MITOTIC recombination can be induced in Saccharomyces cerevisiae by exposing them to ultra-violet and X-radiation1. The genetic maps so obtained closely parallel those from meiotic recombination2. One of the most useful features of mitotic recombination is that it is relatively easy to observe intracistronic recombination. It is possible that this results from a mechanism somewhat different from that leading to meiotic recombination characteristic of higher organisms. For this reason, we decided to study the effects of certain chemical mutagens on the process of mitotic recombination in the hope of being able ultimately to compare these results with those obtained in more usual systems.

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Authors and Affiliations

  1. Department of Biology, Amherst College, Amherst, Massachusetts

    HENRY T. YOST JUN., ROY S. CHALEFF & JAMES P. FINERTY

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  1. HENRY T. YOST JUN.
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  2. ROY S. CHALEFF
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  3. JAMES P. FINERTY
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YOST, H., CHALEFF, R. & FINERTY, J. Induction of Mitotic Recombination in Saccharomyces cerevisiae by Ethyl Methane Sulphonate. Nature 215, 660–661 (1967). https://doi.org/10.1038/215660a0

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