Abstract
THE clinical effect of mescaline is very variable both between different subjects and in the same subject at various times. One factor that has been noted to play a part here is the anxiety proneness of the subject. Klerman1 has shown in a double blind study that passive, anxious, intellectual introverts react in a far more psychotic manner to mescaline than do non-anxious extroverts. Our clinical experience confirms this.
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References
Klerman, G. L., in Trans. Sixth Res. Conf. on Co-operative Chemotherapy Studies in Psychiatry and Broad Research Approaches to Mental Illness, Washington, 339 (1961).
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SMYTHIES, J., BRADLEY, R. & JOHNSTON, V. Interaction of “Stress” and the Response to Mescaline. Nature 215, 1179–1180 (1967). https://doi.org/10.1038/2151179a0
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DOI: https://doi.org/10.1038/2151179a0
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