Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Interaction of “Stress” and the Response to Mescaline

Abstract

THE clinical effect of mescaline is very variable both between different subjects and in the same subject at various times. One factor that has been noted to play a part here is the anxiety proneness of the subject. Klerman1 has shown in a double blind study that passive, anxious, intellectual introverts react in a far more psychotic manner to mescaline than do non-anxious extroverts. Our clinical experience confirms this.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Klerman, G. L., in Trans. Sixth Res. Conf. on Co-operative Chemotherapy Studies in Psychiatry and Broad Research Approaches to Mental Illness, Washington, 339 (1961).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

SMYTHIES, J., BRADLEY, R. & JOHNSTON, V. Interaction of “Stress” and the Response to Mescaline. Nature 215, 1179–1180 (1967). https://doi.org/10.1038/2151179a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2151179a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing