Abstract
THE tapeworm, Hymenolepis nana, produces several exoantigens while infecting the mouse host1, and as a result immune globulins are formed which become available to the parasite in situ2. Present investigations indicate that three of these antigens possess β-naphthyl acetate esterase activity. They appear to be rapidly formed and released by adult worms and to be shared by immature forms as well. This investigation suggests that anti-enzymes are formed locally, as well as systemically, by immunologically competent cells of the mouse ileum. Antibodies engendered do not react against the active sites of the enzymes noted.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Coleman, R. M., and deSa, L. M., Nature, 204, 397 (1964).
Coleman, R. M., and Fotorny, N. M., Nature, 195, 920 (1962).
Perlmann, P., and Hultin, T., Nature, 182, 1530 (1958).
Uriel, J., Ann. N.Y. Acad. Sci., 103, 956 (1963).
Thind, K. S., Immunology, 11, 59 (1966).
Cinader, B., Ann. N.Y. Acad. Sci., 103, 495 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
COLEMAN, R., VENUTA, F. & FIMIAN, W. Secretion and Immunogenicity of Dwarf Tapeworm Esterases. Nature 214, 593–594 (1967). https://doi.org/10.1038/214593a0
Issue Date:
DOI: https://doi.org/10.1038/214593a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.