Letter | Published:

Binding of Tetracycline to Mammalian Spermatozoa

Naturevolume 214pages403404 (1967) | Download Citation



TETRACYCLINES are distributed to various body tissues1, which includes human prostatic fluid2,3 and semen3. Oxytetracycline has been used as a fluorescent stain for condensed spermatid nuclei of the rat4. Tetracycline HCl is a known fluorophor, and so we designed in vitro and in vivo experiments to determine, by fluorescent microscopy, whether this antibiotic binds to spermatozoa.

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  1. Biochemical Research, The Upjohn Company, Kalamazoo, Michigan

    • R. J. ERICSSON
    •  & V. F. BAKER


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