Letter | Published:

Binding of Tetracycline to Mammalian Spermatozoa

Naturevolume 214pages403404 (1967) | Download Citation

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Abstract

TETRACYCLINES are distributed to various body tissues1, which includes human prostatic fluid2,3 and semen3. Oxytetracycline has been used as a fluorescent stain for condensed spermatid nuclei of the rat4. Tetracycline HCl is a known fluorophor, and so we designed in vitro and in vivo experiments to determine, by fluorescent microscopy, whether this antibiotic binds to spermatozoa.

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References

  1. 1

    Milch, R. A., Rall, D. P., and Tobie, J. E., J. Bone Joint Surg., 40 A, 897 (1958).

  2. 2

    Schatten, W. E., and Persky, L., Surgery Gynec. Obstet., 98, 40 (1954).

  3. 3

    Borski, A. A., Pulaski, E. J., Kimbrough, J. C., and Fusillo, M. H., Antibiotics Chemother, 4, 905 (1954).

  4. 4

    Kormano, M., Mikroskopie, 19, 273 (1964).

  5. 5

    Hancock, J. L., Vet. Rec., 69, 996 (1957).

  6. 6

    Fawcett, D. W., Intern. Rev. Cytol., 7, 195 (1958).

  7. 7

    Hancock, J. L., J. Royal Microsc. Soc., 76, 84 (1957).

  8. 8

    Ericsson, R. J., Dutt, R. H., and Archdeacon, J. W., Nature, 204, 261 (1964).

  9. 9

    Chulski, T., Johnson, R. H., Schlagel, C. A., and Wagner, J. G., Nature, 198, 450 (1963).

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Affiliations

  1. Biochemical Research, The Upjohn Company, Kalamazoo, Michigan

    • R. J. ERICSSON
    •  & V. F. BAKER

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https://doi.org/10.1038/214403a0

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