Abstract
ALTHOUGH oxyhaemoglobin is oxidized by nitrite to methaemoglobin, carboxyhaemoglobin is not. This difference can be used to demonstrate the presence of carboxyhaemoglobin in single erythrocytes of a blood smear, simply by extending the methaemoglobin- (cyanmethaemoglobin-) elution technique of Kleihauer and Betke1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kleihauer, E., and Betke, K., Nature, 199, 1196 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BETKE, K., KLEIHAUER, E. Cytological Demonstration of Carboxyhaemoglobin in Human Erythrocytes. Nature 214, 188–189 (1967). https://doi.org/10.1038/214188a0
Issue Date:
DOI: https://doi.org/10.1038/214188a0
This article is cited by
-
The onset of p53-dependent apoptosis plays a role in terminal differentiation of human normoblasts
Oncogene (2003)
-
The effect of inosine on the redistribution of CO between human erythrocytes
Blut Zeitschrift für die Gesamte Blutforschung (1971)
-
Distribution of HbCO in Human Erythrocytes following Inhalation of CO
Nature (1970)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
