Letter | Published:

Effects of Extracts from Thymus on Homograft Survival in Rats

Naturevolume 214pages181183 (1967) | Download Citation

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Abstract

NUMEROUS investigators have reported the effects of neonatal thymectomy on immunological responses1–4. Immunological competence has been restored by implanting thymic grafts1, by inserting a cell tight chamber containing thymus into the intraperitoneal cavity of the thymectomized animal5,6 by injecting whole cells from spleen or thymus7 and by injecting a cell free extract of thymus8. None of these methods provided unequivocal evidence for the cellular origin of the active factor from thymus.

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Affiliations

  1. Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts

    • WILLA BRUNKHORST
    •  & AILENE HERRANEN

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https://doi.org/10.1038/214181b0

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