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Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster

Abstract

ONE of the more intensively studied phenomena used in investigating the control of gene activity in higher organisms is the “puffing” of the polytene chromosomes of Diptera, a phenomenon which has been shown to be an expression of gene activity1. The changing pattern of puffs during larval and prepupal development in Chironomus and Drosophila is influenced, to a certain extent, by the hormone ecdysone2,3. There is evidence that the effect of this hormone is indirect, acting by way of a control of the ionic composition of the cell and nuclear sap4–6.

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ASHBURNER, M. Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster. Nature 214, 1159–1160 (1967). https://doi.org/10.1038/2141159b0

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