It is extremely difficult to create suitable conditions for the investigation of phagocytosis in vitro. A method for comparing uptake of opsonized and unopsonized particles has been developed. It involves the use of monolayers of human neutrophils and mushroom spores.
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NEWSOME, J. Phagocytosis by Human Neutrophils. Nature 214, 1092–1094 (1967). https://doi.org/10.1038/2141092a0
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