Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Localization of Radioiodinated Endotoxin in Organs of Mice and Rabbits: Effect of Thorotrast, Trypan Blue, Endotoxin and Carbon administered intravenously

Abstract

THE splenic uptake of intravenously introduced sheep erythrocyte stroma in mice is increased if certain finely divided agents (carbon, trypan blue, saccharated iron oxide, thorotrast, polystyrene latex) are injected by the same route simultaneously or before the administration of the stroma1. It seemed of interest to investigate whether the distribution of endotoxin in organs was altered in similar conditions.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Fisher, S., Immunology, 11, 127 (1966).

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Ribi, E., Haskins, W. T., Landy, M., and Milner, K. C., J. Exp. Med., 114, 647 (1961).

    Article  CAS  Google Scholar 

  3. Greenwood, F. C., Hunter, W. M., and Glover, J. S., Biochem. J., 89, 114 (1963).

    Article  CAS  Google Scholar 

  4. Doctor, V. M., Proc. Soc. Exp. Biol. Med., 110, 181 (1962).

    Article  CAS  Google Scholar 

  5. Lipner, H. J., Wagner, B. P., and Morris, H. P., Fed. Proc., 13, 465 (1954).

    Google Scholar 

  6. McKay, D. G., Fed. Proc., 22, 1373 (1963).

    CAS  PubMed  Google Scholar 

  7. Good, R. A., and Thomas, L., J. Exp. Med., 96, 625 (1952).

    Article  CAS  Google Scholar 

  8. Thomas, L. in Physiopathology of the Reticulo-endothelial System, 226 (Blackwell, Oxford, 1957).

    Google Scholar 

  9. Margaretten, W., Zunker, H. O., and McKay, D. G., Lab. Invest., 13, 552 (1964).

    CAS  PubMed  Google Scholar 

  10. Howard, J. G., Rowley, D., and Wardlaw, A. C., Immunology, 1, 181 (1958).

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Smith, R. T., Braude, A. I., and Carey, F. J., J. Clin. Invest., 36, 695 (1957).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

FISHER, S. Localization of Radioiodinated Endotoxin in Organs of Mice and Rabbits: Effect of Thorotrast, Trypan Blue, Endotoxin and Carbon administered intravenously. Nature 213, 511–512 (1967). https://doi.org/10.1038/213511a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/213511a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing