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Effect of Two Diuretic Drugs on Liquid Consumption and Free Choice of Alcohol in Albino Rats

Abstract

EARLIER experiments in our laboratories1 with animals on a free choice between water and an ethyl alcohol solution have indicated that the amount of alcohol consumed relative to the total fluid intake, the so-called alcohol preference, is influenced by the water requirement of the animal and by its ability to metabolize alcohol. This means that the absolute amount of alcohol per unit of body weight remains unchanged when the concentration of the alcohol solution is changed. On the other hand, an increasing water requirement may change the calculated alcohol preference, even if the absolute amount of alcohol remains unchanged.

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References

  1. Arvola, A., and Forsander, O., Quart. J. Studies Alc., 24, 591 (1963).

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  2. Parisella, R. M., and Pritham, G. H., Quart. J. Studies Alc., 25, 248 (1964).

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  3. Wallgren, H., and Forsander, O., Brit. J. Nutrit. 17, 453 (1963).

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ERIKSSON, K. Effect of Two Diuretic Drugs on Liquid Consumption and Free Choice of Alcohol in Albino Rats. Nature 213, 316–317 (1967). https://doi.org/10.1038/213316a0

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