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Significance of the Co-existence of Friend Virus in “Friend Tumour”

Abstract

RECENTLY, the presence of tumour specific antigens in viral tumour cells of animals, which can be detected by the virus-neutralization and complement fixation reactions with immune serum against the causal virus, has come to be recognized1. Even when the presence of virus particles in the tumour cannot be proved, it is possible to surmise the presence of the virus genome in some form or other.

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References

  1. Huebner, R. J., Rowe, W. P., Turner, H. C., and Lane, W. T., Proc. U.S. Nat. Acad. Sci., 50, 379 (1963).

    Article  ADS  CAS  Google Scholar 

  2. Buffett, R. F., and Furth, J., Cancer Res., 19, 1063 (1959).

    CAS  PubMed  Google Scholar 

  3. Friend, C., and Haddad, J. R., J. Nat. Cancer Inst., 25, 1279 (1960).

    CAS  PubMed  Google Scholar 

  4. Dawson, P. J., Fieldsteel, A. H., and Bostick, W. L., Cancer Res., 23, 349 (1963).

    CAS  PubMed  Google Scholar 

  5. Mirand, E. A., and Grace, J. T., Accad. Naz. dei Lincei, Quaderno 65, 9 (1964).

  6. Kasuga, T., and Oota, K., Gann no Rinsyo, 8, 251 (1961).

    Google Scholar 

  7. Kobayashi, H., Acta Path. Jap., 16, 79 (1966).

    CAS  PubMed  Google Scholar 

  8. Fieldsteel, H. A., Dawson, P. J., and Scholler, J., J. Nat. Cancer Inst., 36, 71 (1966).

    CAS  PubMed  Google Scholar 

  9. Hanafusa, H., Hanafusa, T., and Rubin, H., Proc. U.S. Nat. Acad. Sci, 49, 572 (1963).

    Article  ADS  CAS  Google Scholar 

  10. Dougherty, R. M., and Di Stefano, S. H., Virology, 27, 351 (1965).

    Article  CAS  Google Scholar 

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KOBAYASHI, H., KODAMA, T. & ITOH, T. Significance of the Co-existence of Friend Virus in “Friend Tumour”. Nature 212, 939–940 (1966). https://doi.org/10.1038/212939b0

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  • DOI: https://doi.org/10.1038/212939b0

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