Letter | Published:

Citrate Condensing Enzyme in Citrus Fruit

Naturevolume 212pages506507 (1966) | Download Citation



CITRATE condensing enzyme has been demonstrated in a wide variety of living tissues: animal tissues1–3, molds4, bacteria1,5,6, and higher plants7,8. It is somewhat surprising that there has been no direct demonstration of its occurrence in citrus fruits. There is no reason to doubt the existence of the enzyme because isolated mitochondria from many plant sources including citrus fruit9 carried out the overall reactions of the Krebs cycle. None the less, we thought it worth while to demonstrate directly its presence in citrus fruit.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Ochoa, S., Stern, J. R., and Schneider, M. C., J. Biol. Chem., 193, 691 (1951).

  2. 2

    Stern, J. R., in The Enzymes, second ed., edit. by Boyer, P., Lardy, H., and Myrback, K., 5, 367 (Academic Press, New York, 1961).

  3. 3

    Srere, P. A., and Kosicki, G. W., J. Biol. Chem., 236, 2559 (1961).

  4. 4

    Ramakrishnan, C. V., and Martin, S. M., Canad. J. Biochem. Physiol., 32, 434 (1954).

  5. 5

    Novelli, G. D., and Lipmann, F., J. Biol. Chem., 182, 213 (1950).

  6. 6

    Goldman, D. S., J. Bacteriol., 73, 602 (1957).

  7. 7

    Deshpandes, W. M., and Ramakrishnan, C. V., J. Biol. Chem., 234, 1929 (1959).

  8. 8

    Hiatt, A. J., Plant Physiol., 37, 85 (1962).

  9. 9

    Bogin, E., and Erickson, L. C., Plant Physiol., 40, 566 (1965).

  10. 10

    Srere, P. A., Brazil, H., and Gonen, L., Acta Chem. Scand., 17, S129 (1963).

  11. 11

    Stern, J. R., Ochoa, S., and Lynen, F., J. Biol. Chem., 198, 313 (1952).

  12. 12

    Lioret, C., and Moyse, A., in Comparative Biochemistry, edit. by Florkin, M., and Mason, H. S., 5, 268, 269 (Academic Press, New York, 1961).

Download references

Author information

Author notes


    Present address: Veterans Administration Hospital, Dallas, Texas


  1. Bio-Medical Research Division, University of California, Lawrence Radiation Laboratory, Livermore, California

    •  & JEAN SENKIN


  1. Search for PAUL A. SRERE in:

  2. Search for JEAN SENKIN in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.