Letter | Published:

Formation of Pyrrolic Compounds by Ultra-violet Irradiation of δ-Aminolevulinic Acid

Nature volume 212, pages 401402 (22 October 1966) | Download Citation

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Abstract

STUDY of the abiogenic formation of biologically important compounds under primitive Earth conditions has led us to suggest the probable path of synthesis of porphine-like substances1ad. This hypothesis proposes that porphines and porphine-like substances were formed spontaneously by condensation of pyrroles and aldehydes. A similar scheme has also been suggested by Krasnovskii2. The aldehyde, one of the required starting materials for this spontaneous synthesis, has been found as a product of the exposure of Urey's atmosphere to electrical discharges3a,b. The other primitive reactant, pyrrole, was assumed to be present, since acetylene and ammonia under primitive Earth conditions would form pyrroles by the action of electrical discharges4.

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Affiliations

  1. Department of Chemistry, University of Detroit, Detroit, Michigan.

    • ANTON SZUTKA

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DOI

https://doi.org/10.1038/212401a0

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