Letter | Published:

A Sialoglycopeptide liberated from Human Red Cells by Treatment with Trypsin

Naturevolume 212pages198199 (1966) | Download Citation

Subjects

Abstract

PREVIOUSLY1, it was shown that treatment of human red cells with crystalline trypsin in a low concentration resulted in destruction of the I agglutinogen on their cells and release of a sialoglycopeptide with the I activity. This communication describes the isolation and some chemical properties of the sialoglycopeptide.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Ohkuma, S., and Ikemoto, S., Proc. Japan Acad., 41, 482 (1965).

  2. 2

    Ohkuma, S., Shinohara, T., and Miyauchi, C., Nature, 207, 527 (1965).

  3. 3

    Ohkuma, S., Shinohara, T., and Miyauchi, C., Proc. Japan Acad., 41, 332 (1965).

  4. 4

    McGuckin, W. F., and McKenzie, B. F., Clin. Chem., 4, 476 (1958).

  5. 5

    Grassmann, W., and Hannig, K., Hoppe-Seyler's Z. Physiol. Chem., 290, 1 (1952).

  6. 6

    Jeanes, A., Wise, C. S., and Dimler, R. J., Anal. Chem., 23, 415 (1951).

  7. 7

    Eylar, E. H., and Jeanloz, R. W., J. Biol. Chem., 237, 622 (1962).

  8. 8

    Ohkuma, S., and Shinohara, T., Nature, 202, 593 (1964).

  9. 9

    Svennerholm, E., and Svennerholm, L., Nature, 181, 1154 (1958).

  10. 10

    Gottschalk, A., and Graham, E. R. B., Biochim. Biophys. Acta, 34, 380 (1959).

  11. 11

    Cook, G. M. W., Heard, D. H., and Seaman, G. V. F., Nature, 188, 1011 (1960).

  12. 12

    Cook, G. M. W., Nature, 195, 159 (1962).

  13. 13

    Eylar, E. H., and Madoff, M. A., Fed. Proc., 21, 402 (1962).

  14. 14

    Marcus, D. M., Kabat, E. A., and Rosenfield, R. E., J. Exp. Med., 118, 175 (1963).

  15. 15

    Iseki, S., and Okada, S., Proc. Japan Acad., 27, 455 (1951).

Download references

Author information

Affiliations

  1. Laboratories of Biochemistry and Serology, National Research Institute of Police Science, Chiyoda-ku, Tokyo, Japan

    • SEIICHI OHKUMA
    •  & SHIGENORI IKEMOTO

Authors

  1. Search for SEIICHI OHKUMA in:

  2. Search for SHIGENORI IKEMOTO in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/212198a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.