Abstract
WHEN adenosine diphosphate (ADP) or thrombin is added to human platelets in plasma the platelets aggregate and some ADP is metabolized1,2, but it is not yet clear which metabolic pathway is involved. Incubation for 30 min with 10−3 molar iodoacetate prevents platelet aggregation but cyanide does not, and it might therefore have been thought that only the glycolytic pathway was involved in the membrane changes leading to platelet aggregation.
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O'BRIEN, J. Changes in Platelet Membranes possibly associated with Platelet Stickiness. Nature 212, 1057–1058 (1966). https://doi.org/10.1038/2121057a0
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DOI: https://doi.org/10.1038/2121057a0
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