Abstract
N-HYDROXYURETHANE is known to be a carcinogen and to induce certain chromosomal aberrations1,2. It contains the hydroxamic acid group, a moiety apparently essential for the antitumour activity of hydroxyurea and its congeners3,4. For this reason, it was considered of interest to determine whether N-hydroxyurethane was active against various transplantable mouse tumours.
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References
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Kelly, M. (personal communication).
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HAHN, M., BOTKIN, C. & ADAMSON, R. Antitumour Activity of N-Hydroxyurethane. Nature 211, 984–985 (1966). https://doi.org/10.1038/211984a0
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DOI: https://doi.org/10.1038/211984a0
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