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Staining of Paneth Cells with Thioflavine T

Abstract

SINCE the thioflavine T (T.T.) fluorochrome method1 was first recommended for the demonstration of amyloid its use has been extended widely. Uptake of the dye has been shown to occur with myeloma casts2, muciphages in the intestinal mucosa3,4, keratin4, mast cells5,6, myelin figures in neurones of infantile amaurotic idiocy and some of the component cells in the granular cell myoblastoma7, acidophils in the pituitary8, juxtaglomerular apparatus cell granules in the kidney6,9 and zymogen granules in the pancreas of mice6.

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BURNS, J., WHITEHEAD, R. Staining of Paneth Cells with Thioflavine T. Nature 211, 769–771 (1966). https://doi.org/10.1038/211769a0

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