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Responses of Thalamic Neurones to Iontophoretically Applied Drugs

Abstract

CLINICAL observations concerning the role of anti-cholinergic drugs1 and ventrolateral thalamotomy2 in the treatment of Parkinson's syndrome, together with histochemical investigations of the distribution of acetylcholinesterase in the thalamus3, particularly in those nuclei relaying ascending reticular afferent fibres, suggest a possible transmitter-function for acetylcholine (ACh) in the ventrobasal thalamic nuclei.

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MCCANCE, I., PHILLIS, J. & WESTERMAN, R. Responses of Thalamic Neurones to Iontophoretically Applied Drugs. Nature 209, 715–716 (1966). https://doi.org/10.1038/209715a0

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