Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

High Content of Hyaluronic Acid in Normal Human Heart Valves

Abstract

DURING the course of investigations of the effect of age on acid mucopolysaccharide content of the human heart valves, we found hyaluronic acid to be a major component. In all it represented about 60 per cent of the acid mucopolysaccharide present in the tissue. This observation is in striking contrast with reports from other laboratories1,2 which have shown hyaluronic acid to be a minor component of both bovine and pig heart valves. This communication reports the distribution of the acid mucopolysaccharide fractions of the normal human heart valves.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Moretti, A., and Whitehouse, M. W., Biochem. J., 87, 396 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Meyer, K., Davidson, E., Linker, A., and Hoffman, P., Biochim. Biophys. Acta, 21, 506 (1956).

    Article  CAS  PubMed  Google Scholar 

  3. Schiller, S., Slover, G. A., and Dorfman, A., J. Biol. Chem., 236, 983 (1961).

    CAS  PubMed  Google Scholar 

  4. Dische, Z., J. Biol. Chem., 167, 189 (1947).

    CAS  PubMed  Google Scholar 

  5. Stoffyn, P. J., and Jeanloz, R. W., Arch. Biochem. Biophys., 52, 373 (1954).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

TORII, S., BASHEY, R. High Content of Hyaluronic Acid in Normal Human Heart Valves. Nature 209, 506–507 (1966). https://doi.org/10.1038/209506b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/209506b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing