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High Content of Hyaluronic Acid in Normal Human Heart Valves


DURING the course of investigations of the effect of age on acid mucopolysaccharide content of the human heart valves, we found hyaluronic acid to be a major component. In all it represented about 60 per cent of the acid mucopolysaccharide present in the tissue. This observation is in striking contrast with reports from other laboratories1,2 which have shown hyaluronic acid to be a minor component of both bovine and pig heart valves. This communication reports the distribution of the acid mucopolysaccharide fractions of the normal human heart valves.

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TORII, S., BASHEY, R. High Content of Hyaluronic Acid in Normal Human Heart Valves. Nature 209, 506–507 (1966).

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