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A Factor inhibiting the Adenosine Triphosphatase Activity and the Superprecipitation of Actomyosin

Nature volume 209, pages 1352–1353 (1966)Cite this article

Abstract

EBASHI1 has produced evidence for a protein factor in the presence of which the magnesium-activated ATPase2 and the superprecipitation1 of actomyosin are inhibited by low concentrations of ethylene bis(NN′diacetyl β amino ethyl) ether (EGTA). To observe the effect of this factor the actomyosin was prepared from separately purified actin and myosin, so-called ‘synthetic’ actomyosin. We have obtained similar effects with an actomyosin preparation extracted as the complex from muscle and treated by a procedure described elsewhere3. This preparation is referred to in this communication as desensitized actomyosin.

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Authors and Affiliations

  1. Department of Biochemistry, University of Birmingham,

    D. J. HARTSHORNE, S. V. PERRY & VALERIE DAVIES

Authors
  1. D. J. HARTSHORNE
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  2. S. V. PERRY
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  3. VALERIE DAVIES
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HARTSHORNE, D., PERRY, S. & DAVIES, V. A Factor inhibiting the Adenosine Triphosphatase Activity and the Superprecipitation of Actomyosin. Nature 209, 1352–1353 (1966). https://doi.org/10.1038/2091352a0

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