Abstract
EARLY attempts to isolate an endotoxin from Pasteurella pestis by most classical methods have failed. Recently Davies1 isolated a lipopolysaccharide containing a heptose and phospholipid by extraction in hot phenol water. Cocking et al.2 produced a similar toxin by the use of ultra-sound and purification by column chromatography. These workers also reported briefly on the pathology produced by their toxins.
Similar content being viewed by others
Article PDF
References
Davies, D. A. L., Biochem. J., 63, 105 (1956).
Cocking, E. C., Keppie, J., Witt, K., and Smith, H., Brit. J. Exp. Pathol., 61, 460 (1960).
Dische, Z., J. Biol. Chem., 204, 983 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WALKER, R., BARNES, M. & HIGGINS, E. Composition of and Physiopathology produced by Plague Endotoxins. Nature 209, 1246 (1966). https://doi.org/10.1038/2091246a0
Issue Date:
DOI: https://doi.org/10.1038/2091246a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.