Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Determination of Serum Oxytocinase (l-Cystine-aminopeptidase) Activity

Abstract

AN increasing interest is being shown in serum oxyto-cinase (l-cystine-aminopeptidase (3.4.1.2.)) levels in pregnancy, yet the methods described in recent papers1,2 for its determination seem unnecessarily laborious. We have for some time now been using the modification described here. It is based on the method used for the determination of l-leucine-aminopeptidase (3.4.1.1.) activity in serum3–5, now used as a routine biochemical investigation for which commercial test kits have been developed, such as that of Boehringer, Biochemica, Mannheim, which we use.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Titus, M. A., Reynolds, D. R., Glendening, M. B., and Page, E. W. C., Amer. J. Obst. Gynec., 80, 1124 (1960).

    Article  CAS  Google Scholar 

  2. Klimek, R., and Bietrzycka, M., Clin. Chim. Acta, 6, 326 (1960).

    Article  Google Scholar 

  3. Braun-Falco, O., and Salfeld, K., Arch. Klin. Exp. Derm., 204, 407 (1957).

    Article  CAS  Google Scholar 

  4. Green, M. N., Tsou, K., Bressler, R., and Seligman, A. M., Arch. Biochem. Biophys., 57, 458 (1955).

    Article  CAS  Google Scholar 

  5. Brente, E., and Bergmeyer, H. U., Methods in Enzymatic Analysis, 833 (Verlag Chemie/Academic Press, 1963).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

HARDY, S., RITCHIE, J. Determination of Serum Oxytocinase (l-Cystine-aminopeptidase) Activity. Nature 209, 76–77 (1966). https://doi.org/10.1038/209076a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/209076a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing