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Diurnal Variations in Ovarian Ascorbic Acid Content of Pseudopregnant Immature Rats used in Parlow's Test

Nature volume 208, pages 789–790 (1965)Cite this article

Abstract

DEPLETION of ascorbic acid from the ovary of the immature rat rendered pseudopregnant by treatment with pregnant mare's serum (PMS) and human chorionic gonadotrophin (HCG) is used as an assay for luteinizing hormone (LH). A significant diurnal variation in the ovarian ascorbic acid (OAA) content was observed by Stevens1 in such rats. These variations may be important in the assay of LH by Parlow's method.

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Authors and Affiliations

  1. Laboratorio de Fisiología, Escuela de Medicina, Universidad Católica, Santiago de Chile

    M. DE LA LASTRA & H. CROXATTO

Authors
  1. M. DE LA LASTRA
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  2. H. CROXATTO
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DE LA LASTRA, M., CROXATTO, H. Diurnal Variations in Ovarian Ascorbic Acid Content of Pseudopregnant Immature Rats used in Parlow's Test. Nature 208, 789–790 (1965). https://doi.org/10.1038/208789a0

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