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Differentiation between Cytophilic Antibody and Opsonin by a Macrophage Phagocytic System

Nature volume 208, pages 594–595 (1965)Cite this article

Abstract

OPSONIC antibody by combining specifically with antigen facilitates ingest ion of that antigen by leucocytes. Recently, a cytophilic antibody has been described which becomes attached to mammalian cells in vitro in such a way that antigen is specifically adsorbed1,2. The investigation reported here was made to compare the ability of these two types of antibody to potentiate phagocytosis.

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References

  1. Boyden, S. V., and Sorkin, E., Immunology, 3, 272 (1960); 4, 244 (1961).

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Sorkin, E., in The Immunologically Competent Cell, edit. by Wolstenholme, G. E. W., 38 (Churchill Ltd., 1963).

    Google Scholar 

  3. Marrack, J. R., Hoch, H., and Johns, R. G. S., Brit. J. Exp. Path., 32, 212 (1951).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Tee, D. E. H., Watkins, J., Wang, M., Gammack, D. B., and Raper, J. H., Immunology (in the press).

  5. Ovary, Z., Benacerraf, B., and Bloch, K. J., J. Exp. Med., 117, 951 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Boyden, S. V., J. Exp. Med., 93, 107 (1951).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Gordon, J., Rose, B., and Sehon, A. H., J. Exp. Med., 108, 37 (1958).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Middlebrook, G., and Dubos, R. G., J. Exp. Med., 88, 521 (1948).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Ovary, Z., J. Immunol., 81, 355 (1958).

    CAS  PubMed  Google Scholar 

  10. Fahey, J. L., Wunderlich, J., and Mishell, R., J. Exp. Med., 120, 223 (1964). Nussenzweig, R. S., Merryman, C., and Benacerraf, B., J. Exp. Med., 120, 315 (1964).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Keller, R., and Sorkin, E., Nature, 199, 709 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  12. Turner, K. J., Jenkin, C. R., and Rowley, D., Austral. J. Exp. Biol. and Med. Sci., 42, 229 (1964). Rowley, D., Turner, K. J., and Jenkin, C. R., ibid., 42, 237 (1964).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Lister Institute of Preventive Medicine, London, S.W.1.

    W. E. PARISH

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  1. W. E. PARISH
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PARISH, W. Differentiation between Cytophilic Antibody and Opsonin by a Macrophage Phagocytic System. Nature 208, 594–595 (1965). https://doi.org/10.1038/208594a0

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