Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Failure of the Zona Reaction in Five Pig Eggs

Abstract

IN most mammals which have been examined, the first spermatozoon that penetrates into the egg stimulates the egg to undergo a reaction which prevents subsequent spermatozoa from traversing the zona pellucida1. This phenomenon is called the ‘zona reaction’. In the pig, following the zona reaction, spermatozoa can still penetrate into the zona but they normally cannot traverse it2. However, eggs aged for several hours before exposure to the first spermatozoon sometimes fail to elicit the zona reaction and several spermatozoa enter the vitellus (polyspermy) to become male pronuclei (polyandry)3.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Braden, A. W. H., Austin, C. R., and David, H. A., Austral. J. Biol. Sci., 7, 391 (1954).

    Article  CAS  Google Scholar 

  2. Dickmann, Z., and Dziuk, P. J., J. Exp. Biol., 41, 603 (1964).

    CAS  PubMed  Google Scholar 

  3. Hancock, J. L., Animal Prod., 1, 103 (1959).

    Article  Google Scholar 

  4. Hancock, J. L., J. Reprod. Fertil., 2, 307 (1961).

    Article  CAS  Google Scholar 

  5. Polge, C., and Dziuk, P. J., J. Reprod. Fertil., 9, 357 (1965).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

DZIUK, P., DICKMANN, Z. Failure of the Zona Reaction in Five Pig Eggs. Nature 208, 502–503 (1965). https://doi.org/10.1038/208502b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/208502b0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing