Abstract
MORE than eighty years ago, Ringer1 observed that rubidium ions had effects on the frog's ventricles similar to those produced by potassium. Since then these two ions have been found to be very nearly interchangeable in a wide variety of biochemical and physiological processes2.
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References
Ringer, S., J. Physiol., 4, 370 (1882).
Relman, A., Yale J. Biol. and Med., 29, 248 (1956).
Relman, A., Lambie, A., Burrows, B., and Roy, A., J. Clin. Invest., 36, 1249 (1957).
Lambie, A., Relman, A., and Schwartz, W., J. Clin. Invest., 38, 1538 (1958).
Kunin, A., Dearborn, E., Burrows, B., and Relman, A., Amer. J. Physiol., 197, 1297 (1959).
Solomon, A., J. Gen. Physiol., 36, 57 (1952).
Love, W., and Burch, G., J. Lab. and Clin. Med., 41, 351 (1953).
Kahn, J., J. Pharm. and Exp. Therap., 136, 197 (1962).
Hilton, J., Weaver, D., Muelheims, G., Glaviano, V., and Wegria, R., Amer. J. Physiol., 192, 525 (1958).
Davis, J., Urquhart, J., and Higgins, J., J. Clin. Invest., 42, 597 (1963).
Kunin, A., Dearborn, E., and Relman, A., Amer. J. Physiol., 183, 636 (1955).
Tarail, R., Bennett, T., and Noell, W., J. Clin. Invest., 34, 966 (1955).
Glasser, L., and Ellis, J., Amer. J. Path., 38, 103 (1961).
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HILTON, J., ALTER, S. & CUSHMAN, P. Aldosterone Secretion : Differences in Direct Effects of Rubidium and Potassium Perfusion into Dog Adrenals. Nature 208, 1099–1100 (1965). https://doi.org/10.1038/2081099a0
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DOI: https://doi.org/10.1038/2081099a0
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