Abstract
IN attempting to identify trace amounts of metabolites from biological fluids, the use of one of the most powerful tools of organic chemical analysis, infra-red spectroscopy, presents technical difficulties. The two major ones are: (a) a sample preparation technique for the characteristically polar compounds, and (b) sufficient purity to allow a resolvable spectrum.
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MANDELL, A. Simultaneous Chromatographic Separation and Infra-red Sample Preparation of Indole Acids. Nature 207, 977–978 (1965). https://doi.org/10.1038/207977a0
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DOI: https://doi.org/10.1038/207977a0
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