Abstract
THE cell cycle in proliferating mammalian tissues in adult animals commonly takes from 10 to 20 h. The DNA synthetic period (S) is fairly constant between 5 and 9 h and the post-DNA synthetic period (G2) is usually 1–2 h in duration. Most of the variability comes during the pre-DNA synthetic period (G1), although exceptions to this rule are known1. Among the shortest cycle times yet reported are those found in the normal and resected rat gut (8.2–9.4 h) (ref. 2), in the chronically irradiated mouse gut (∼8 h) (refs. 3 and 4) and in the neural tube of mouse embryos at 10 days gestation (probably ∼ 6.5 h; ref. 5).
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References
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WIMBER, D., LAMERTON, L. Cell Cycle of Mouse Embryonic Tissue under Continuous Gamma-irradiation. Nature 207, 432–433 (1965). https://doi.org/10.1038/207432a0
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DOI: https://doi.org/10.1038/207432a0
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