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Distribution of Agglutinating Antibodies to Listeria monocytogenes among Vertebrates


INVESTIGATIONS of the host–parasite relationship of Listeria monocytogenes to man and to several species of domestic ungulates have revealed that serum antibodies reactive with the bacterium may be found in a high percentage of apparently normal individuals1. The proper interpretation of these immunological reactions has been a persisting question in serology, particularly since the species concerned are subject to clinical listeriosis. Do the antibodies demonstrate a high level of inapparent infection by a ubiquitous organism wherein few of the attacked individuals experience the clinical disease, or do they arise from antigenic stimuli other than L. monocytogenes and manifest cross-reactivity because heterogenetic antigen systems are involved ?

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OSEBOLD, J. Distribution of Agglutinating Antibodies to Listeria monocytogenes among Vertebrates. Nature 207, 209–210 (1965).

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