Abstract
A DIET containing 0.4 or 1.0 per cent of rutin, a flavonol glycoside with vitamin P activity, has been shown to have no effect on reproduction1,2. However, Cutting et al.3 observed that a diet containing 0.1 per cent rutin significantly impaired the fertility of female mice. Therefore, using carbonic anhydrase determination in the uterine endometrium as an indicator of the progestational proliferation in Clauberg rabbits4, an attempt was made to elucidate whether or not rutin is capable of affecting the progestational proliferation of the rabbit endometrium.
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References
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YAMASHITA, K. Anti-progestational Activity of Rutin on the Rabbit Uterus. Nature 207, 198–199 (1965). https://doi.org/10.1038/207198a0
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DOI: https://doi.org/10.1038/207198a0
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