Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Genetic Code: The ‘Nonsense’ Triplets for Chain Termination and their Suppression

This is a preview of subscription content

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Benzer, S., and Champe, S. P., Proc. U.S. Nat. Acad. Sci., 47, 1025 (1961); 48, 1114 (1962).

    ADS  CAS  Article  Google Scholar 

  2. 2

    Garen, A., and Siddiqi, O., Proc. U.S. Nat. Acad. Sci., 48, 1121 (1962).

    ADS  CAS  Article  Google Scholar 

  3. 3

    Campbell, A., Virology, 14, 22 (1961).

    CAS  Article  Google Scholar 

  4. 4

    Epstein, R. H., Bolle, A., Steinberg, C. M., Kellenberger, E., Boy de la Tour, E., Chevalley, R., Edgar, R. S., Susman, M., Denhardt, G. H., and Lielausis, A., Cold Spring Harbour Symp. Quant. Biol., 28, 375 (1963).

    CAS  Article  Google Scholar 

  5. 5

    Sarabhai, A., Stretton, A. O. W., Brenner, S., and Bolle, A., Nature 201, 13 (1964).

    ADS  CAS  Article  Google Scholar 

  6. 6

    Stretton, A. O. W., and Brenner, S., J. Mol. Biol. (in the press).

  7. 7

    Kaplan, S., Stretton, A. O. W., and Brenner, S. (in preparation).

  8. 8

    Brenner, S., and Beckwith, J. R. (in preparation).

  9. 9

    Brenner, S., and Stretton, A. O. W. (in preparation).

  10. 10

    Brown, D. M., and Schell, P., J. Mol. Biol., 3, 709 (1961). Freese, E., Bautz-Freese, E., and Bautz, E., J. Mol. Biol., 3, 133 (1961). Schuster, H., J. Mol. Biol., 3, 447 (1961). Freese, E., Bautz, E., and Freese, E. B., Proc. U.S. Nat. Acad. Sci., 47, 845 (1961).

    CAS  Article  Google Scholar 

  11. 11

    Tocchini-Valentini, G. P., Stodolsky, M., Aurisicchio, A., Sarnat, M., Graziosi, F., Weiss, S. B., and Geiduschek, E. P., Proc. U.S. Nat. Acad. Sci., 50, 935 (1963). Hayashi, M., Hayashi, M. N., and Spiegelman, S., Proc. U.S. Nat. Acad. Sci., 50, 664 (1963). Marmur, J., Greenspan, C. M., Palacek, E., Kahan, F. M., Levene, J., and Mandel, M., Cold Spring Harbor Symp. Quant. Biol., 28, 191 (1963). Bautz, E. K. F., Cold Spring Harbor Symp. Quant. Biol., 28, 205 (1963). Hall, B. D., Green, M., Nygaard, A. P., and Boezi, J., Cold Spring Harbor Symp. Quant. Biol., 28, 201 (1963).

    ADS  CAS  Article  Google Scholar 

  12. 12

    Champe, S. P., and Benzer, S., Proc. U.S. Nat. Acad. Sci., 48, 532 (1962). Tessman, I., Poddar, R. K., and Kumar, S., J. Mol. Biol., 9, 352 (1964).

    ADS  CAS  Article  Google Scholar 

  13. 13

    Freese, E., J. Mol. Biol., 1, 87 (1959). Freese, E., Proc. U.S. Nat. Acad. Sci., 45, 622 (1959). Howard, B. D., and Tessman, I., J. Mol. Biol., 9, 372 (1964).

    CAS  Article  Google Scholar 

  14. 14

    Garen, A., and Weigert, M. G., J. Mol. Biol. (in the press).

  15. 15

    Notani, G. W., Engelhardt, D. L., Konigsberg, W., and Zinder, N., J. Mol. Biol. (in the press).

  16. 16

    Nirenberg, M., Jones, O. W., Leder, P., Clark, B. F. C., Sly, W. S., and Pestka, S., Cold Spring Harbor Symp. Quant., Biol., 28, 549 (1963).

    CAS  Article  Google Scholar 

  17. 17

    Speyer, J. F., Lengyel, P., Basilio, C., Wahba, A. J., Gardner, R. S., and Ochoa, S., Cold Spring Harbor Symp. Quant. Biol., 28, 559 (1963).

    CAS  Article  Google Scholar 

  18. 18

    Nirenberg, M., Leder, P., Bernfield, M., Brimacombe, R., Trupin, J., and Rottman, F., Proc. U.S. Nat. Acad. Sci. (in the press).

  19. 19

    Stretton, A. O. W., and Brenner, S. (in preparation).

  20. 20

    Trupin, J., Rottman, F., Brimacombe, R., Leder, P., Bernfield, M., and Nirenberg, M., Proc. U.S. Nat. Acad. Sci. (in the press). Clark, B. F. C., presented before the French Biochemical Society, February, 1965.

  21. 21

    Weigert, M. G., and Garen, A., Nature (preceding communication).

  22. 22

    Leder, P., and Nirenberg, M. W., Proc. U.S. Nat. Acad. Sci., 52, 1521 (1964).

    ADS  CAS  Article  Google Scholar 

  23. 23

    Gilbert, W., J. Mol. Biol., 6, 389 (1963). Bretscher, M. S., J. Mol. Biol., 7, 446 (1963).

    CAS  Article  Google Scholar 

  24. 24

    Davies, J., Gilbert, W., and Gorini, L., Proc. U.S. Nat. Acad. Sci., 51, 883 (1964).

    ADS  CAS  Article  Google Scholar 

  25. 25

    Gorini, L., and Kataja, E., Proc. U.S. Nat. Acad. Sci., 51, 487 (1964).

    ADS  CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

BRENNER, S., STRETTON, A. & KAPLAN, S. Genetic Code: The ‘Nonsense’ Triplets for Chain Termination and their Suppression. Nature 206, 994–998 (1965). https://doi.org/10.1038/206994a0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links