Glutaminase Activity and Neocortical Excitability


THE work recorded here was carried out in order to ascertain whether glutaminase I activity in the neocortex of the cat plays a part in the glutamate-glutamine system changes induced by the appearance and development of an epileptogenic focus produced by application of mescaline1.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Mison-Crighel, N., Luca, N., and Crighel, E., J. Neurochem., 11, 333 (1964).

  2. 2

    Errera, E., and Greenstein, J. P., J. Biol. Chem., 178, 495 (1949).

  3. 3

    Pintilie, C., Mison-Crighel, N., and Crighel, E., Stud. Cercet. Neurol., 8, 271 (1963).

  4. 4

    Kritschevskaya, A. A., Gershenovitsch, Z., S. and Scherbatzker Biohimia, 64, 459 (1959).

  5. 5

    Krebs, H. A., Biochem. J., 29, 1951 (1935).

  6. 6

    Waelsch, H., Adv. in Protein Chem., 6, 311 (1951).

  7. 7

    Sayre, F. W., and Roberts, E., J. Biol. Chem., 233, 1128 (1958).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MISON-CRIGHEL, N., PINTILIE, C. & CRIGHEL, E. Glutaminase Activity and Neocortical Excitability. Nature 206, 1257–1258 (1965).

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.