Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effects of Antibiotics on Chromosomes of Cultured Human Leucocytes

Abstract

PENICILLIN and streptomycin have been commonly added to growth media used in the culture of human leucocytes for cytogenetic analysis. Since the literature on human cytogenetics is increasing rapidly, largely through the use of these techniques, it seemed appropriate to examine any possible cytological effects of antibiotics per se on cultured human leucocyte chromosomes or on the mitotic index.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Welch, H., Antibiotic Therapy (Med. Encyclopedia Inc., New York, 1954).

    Google Scholar 

  2. Nichols, W. W., Levan, A., Hall, B., and Ostergren, G., Hereditas, 48, 367 (1962).

    Article  Google Scholar 

  3. Hu, F., Livingood, C. S., Johnson, P., and Pomerat, G. M., J. Inv. Derm., 20, 357 (1953).

    Article  CAS  Google Scholar 

  4. Wilson, G. B., J. Hered., 41, 227 (1950).

    Article  CAS  Google Scholar 

  5. Cohlan, S. Q., Bevelander, G., and Tiamsic, T., Amer. J. Dis. Child., 105 (1963).

  6. Bevelander, G., Nakahara, H., and Rolle, G. K., Nature, 184, 729 (1969).

    Google Scholar 

  7. Charles, D. J., J. Obstet. Gynaec. Bri. Emp., 61, 750 (1954).

    Article  CAS  Google Scholar 

  8. Carter, M. P., and Wilson, F., Lancet, i, 1267 (1963).

  9. Harley, J. D., Farrar, J. F., Gray, J. B., and Dunlop, I. C., Lancet, i, 472 (1964).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

NEU, R., ASPILLAGA, M. & GARDNER, L. Effects of Antibiotics on Chromosomes of Cultured Human Leucocytes. Nature 205, 171–172 (1965). https://doi.org/10.1038/205171a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/205171a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing