Abstract
IT has been previously shown that new-born hamsters are susceptible to the oncogenic effect of polyoma virus1 introduced intracerebrally2. Likewise, S V 40 virus3 which was shown to be oncogenic when injected subcutaneously into new-born hamsters4 also proved capable of inducing papillary ependymomas after intracerebral inoculation into the same animals5. In recent years a variant of the chicken Rous sarcoma virus (RSV), the Schmidt-Ruppin strain6, has been shown to be oncogenic in a variety of subcutaneously inoculated rodents, including hamsters7. The investigation described here was undertaken to determine the effects of intracerebral inoculation of this virus into new-born hamsters.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Stewart, S. E., Eddy, B. E., and Borgese, N. G., J. Nat. Cancer Inst., 20, 1223 (1958).
Rabson, A. S., and Kierschstein, R. L., Arch. Path., 69, 663 (1960).
Sweet, B. H., and Hilleman, M. R., Proc. Soc. Exp. Biol. and Med., 105, 420 (1960).
Eddy, B. E., Borman, G. S., Grubbs, G. E., and Young, R. D., Virology, 17, 65 (1962).
Kirschstein, R. L., and Gerber, P., Nature, 195, 299 (1962).
Schmidt-Ruppin, K. H., Sonderbände zur Strahlentherapie, 41, 3, 26 (1959).
Ahlstrom, C. G., and Forsby, N., J. Exp. Med., 115, 839 (1962).
Moloney, J. B., J. Nat. Cancer Inst., 16, 877 (1956).
Zimmerman, H. M., Netsky, M. G., and Davidoff, L. M., Atlas of Tumors of the Nervous System (Lea and Febiger, Philadelphia, 1956).
Basquez-Lopez, E., Amer. J. Cancer, 26, 29 (1936).
Vigier, P., Bull. Assoc. pour l'étude du Cancer, 44, 409 (1957).
Spencer, H. J., and Groupé, V., J. Nat. Cancer Inst., 29, 397 (1962).
Stewart, H. L., in Physiopathology of Cancer, edit. by Homburger, F., and Fishman, W. H., 84 (P. B. Hoeber, New York, 1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
RABOTTI, G., RAINE, W. Brain Tumours induced in Hamsters inoculated intracerebrally at Birth with Rous Sarcoma Virus. Nature 204, 898–899 (1964). https://doi.org/10.1038/204898a0
Issue Date:
DOI: https://doi.org/10.1038/204898a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.