Letter | Published:

Brain Tumours induced in Hamsters inoculated intracerebrally at Birth with Rous Sarcoma Virus

Nature volume 204, pages 898899 (28 November 1964) | Download Citation

Subjects

Abstract

IT has been previously shown that new-born hamsters are susceptible to the oncogenic effect of polyoma virus1 introduced intracerebrally2. Likewise, S V 40 virus3 which was shown to be oncogenic when injected subcutaneously into new-born hamsters4 also proved capable of inducing papillary ependymomas after intracerebral inoculation into the same animals5. In recent years a variant of the chicken Rous sarcoma virus (RSV), the Schmidt-Ruppin strain6, has been shown to be oncogenic in a variety of subcutaneously inoculated rodents, including hamsters7. The investigation described here was undertaken to determine the effects of intracerebral inoculation of this virus into new-born hamsters.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , , and , J. Nat. Cancer Inst., 20, 1223 (1958).

  2. 2.

    , and , Arch. Path., 69, 663 (1960).

  3. 3.

    , and , Proc. Soc. Exp. Biol. and Med., 105, 420 (1960).

  4. 4.

    , , , and , Virology, 17, 65 (1962).

  5. 5.

    , and , Nature, 195, 299 (1962).

  6. 6.

    , Sonderbände zur Strahlentherapie, 41, 3, 26 (1959).

  7. 7.

    , and , J. Exp. Med., 115, 839 (1962).

  8. 8.

    , J. Nat. Cancer Inst., 16, 877 (1956).

  9. 9.

    , , and , Atlas of Tumors of the Nervous System (Lea and Febiger, Philadelphia, 1956).

  10. 10.

    , Amer. J. Cancer, 26, 29 (1936).

  11. 11.

    , Bull. Assoc. pour l'étude du Cancer, 44, 409 (1957).

  12. 12.

    , and , J. Nat. Cancer Inst., 29, 397 (1962).

  13. 13.

    , in Physiopathology of Cancer, edit. by Homburger, F., and Fishman, W. H., 84 (P. B. Hoeber, New York, 1953).

Download references

Author information

Affiliations

  1. Laboratory of Viral Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

    • GIANCARLO F. RABOTTI
    •  & WIRTLEY A. RAINE

Authors

  1. Search for GIANCARLO F. RABOTTI in:

  2. Search for WIRTLEY A. RAINE in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/204898a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.