Letter | Published:

Metabolic Fate of 2,4-Dichlorophenoxyacetic Acid in the Stem Tissue of Phaseolus vulgaris



IN this Department previous investigations1,2 of the metabolic fate of a series of chlorinated phenoxyacetic acids in stem tissues of Avena sativa have demonstrated that the formation of glucose esters or hydroxylation followed by conversion to a glucoside are major pathways. In this tissue 2,4-dichlorophenoxyacetic acid (2,4-D) is converted principally into 1-0-(2,4-dichlorophenoxyacetyl)-β-D-glucose. In contrast, in the stems of Phaseolus vulgaris the principal metabolite isolated was seemingly a glucoside of a phenolic acid3 which was not a hydroxy-2,4-dichlorophenoxyacetic acid3–5. Further investigation has identified the presence of a mixture of 2,5-dichloro-4-hydroxyphenoxyacetic acid and 2,3-dichloro-4-hydroxyphenoxyacetic acid.

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  1. 1

    Thomas, E. W., Loughman, B. C., and Powell, R. G., Nature, 199, 73 (1963).

  2. 2

    Thomas, E. W., Loughman, B. C., and Powell, R. G., Nature, 204, 286 (1964).

  3. 3

    Thomas, E. W., D.Phil. thesis, Univ. Oxford (1964).

  4. 4

    Holley, R. W., Arch. Biochem. Biophys., 35, 171 (1952).

  5. 5

    Crosby, D. G., J. Agric. Food Chem., 12, 3 (1964).

  6. 6

    Faulkner, J. K., and Woodcock, D., Nature, 203, 865 (1964).

  7. 7

    Conant, J. B., and Fieser, L. F., J. Amer. Chem. Soc., 45, 2204 (1923).

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