Abstract
IT has been found that replication of some myxo-viruses (Sendai and NDV) was stimulated by actinomycin D (refs. 1 and 2) but in influenza and fowl plague viruses multiplication was inhibited by this antibiotic3–5. Based on actinomycin-induced inhibition of influenza hæmagglutinin production, Barry et al.3 concluded that influenza virus RNA synthesis, unlike NDV, requires participation of cell DNA.
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References
Bukrinskaya, A. G., and Zhdanov, V. M., Nature, 200, 920 (1963).
Wheelock, E. F., Proc. Exp. Biol. Med., 114, 1 56 (1963).
Barry, R. D., Ives, D. R., and Cruickshank, J. G., Nature, 194, 1139 (1962).
Zhdanov, V. M., and Bukrinskaya, A. G., Probl. Virol., 2, 230 (1963).
Reich, E., Cancer Res., 23, 8, 1428 (1963).
Zhdanov, V. M., Bukrinskaya, A. G., and Ramenskaya, G. P., Probl. Virol., 5, 564 (1963).
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BUKRINSKAYA, A. Resistance of Synthesis of Influenza Virus Ribonucleic Acid to the Action of Actinomycin D. Nature 204, 205–206 (1964). https://doi.org/10.1038/204205a0
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DOI: https://doi.org/10.1038/204205a0
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