Abstract
2-β-AMINOETHYLISOTHIOUREA (AET)1,2, glutathione3,4 and serotonin5, administered separately, have been shown to protect X-irradiated mice. Many attempts have been made to increase the protective action by combining two or more drugs, and we have shown previously that AET in combination with serotonin increases optimal protection offered by either compound alone6,7. Results are reported here on the survival of mice treated with glutathione, AET and serotonin prior to exposure to a supralethal dose of X-irradiation.
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MAISIN, J. Protection with 2-β-Aminoethylisothiourea, Glutathione and Serotonin of Mice against Whole-body Irradiation. Nature 204, 196–197 (1964). https://doi.org/10.1038/204196a0
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DOI: https://doi.org/10.1038/204196a0
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