Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Location of Renshaw Cells

Abstract

EVER since their discovery1, the mammalian spinal cord interneurones known as ‘Renshaw cells’2 have been the object of extensive physiological and pharmacological research3. The recurrent inhibitory pathway from motor axon collaterals via Renshaw cells back to motoneurones serves as one of the best-documented examples of a negative feed-back mechanism in the central nervous system. Furthermore, the cholinergic synapses made by the motor axon collaterals on Renshaw cells are the most thoroughly analysed central synapses from the point of view of their pharmacology.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Renshaw, B., J. Neurophysiol., 9, 191 (1946).

    Article  CAS  Google Scholar 

  2. Eccles, J. C., Fatt, P., and Koketsu, K., J. Physiol., 126, 524 (1954).

    Article  CAS  Google Scholar 

  3. Granit, R., Pascoe, J. E., and Steg, G., J. Physiol., 138, 381 (1957); Curtis, D. R., and Eccles, R. M., J. Physiol., 141, 435, 446 (1958); Wilson, V. J., Talbot, W. H., and Diecke, F. P. J., J. Neurophysiol., 23, 144 (1960); Eccles, J. C., Eccles, R. M., Iggo, A., and Lundberg, A., J. Physiol., 159, 461 (1961); Eccles, J. C., Eccles, R. M., Iggo, A., and Ito, M., J. Physiol., 159, 479 (1961).

    Article  CAS  Google Scholar 

  4. Sprague, J. M., J. Comp. Neurol., 95, 103 (1951); Szentagothai, J., Acta morph. Acad. Sci. hung., 8, 287 (1958).

    Article  CAS  Google Scholar 

  5. Scheibel, M. E., and Scheibel, A. B., Anat. Rec., 148, 332 (1964); illustrations of some of the Golgi stained interneurones in their study were shown at the seventy-seventh annual meeting of the American Association of Anatomists, Denver, Colorado, 1964.

    Google Scholar 

  6. Galifret, Y., and Szabo, T., Nature, 188, 1033 (1960).

    Article  CAS  Google Scholar 

  7. Rexed, B., J. Comp. Neural., 100, 297 (1954).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

WILLIS, W., WILLIS, J. Location of Renshaw Cells. Nature 204, 1214–1215 (1964). https://doi.org/10.1038/2041214b0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2041214b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing