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Schistosoma mansoni: Humoral Transfer of Protective Factors produced by Irradiated Cercariæ

Abstract

PREVIOUS investigations1,2 have produced information concerning the manner in which prior exposure of mice to irradiated cercariæ of Schistosoma, mansoni affects the course of the challenge infection. The results indicated that the principal effect of the aborted infection with irradiated cercariæ was to slow the migration and development of worms from the challenge infection. The delay in accumulation of recoverable worms and eggs suggested the probability of inhibitory factors being produced by the aborted infection with irradiated cercariæ, although their relation to specific acquired resistance could not be defined.

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References

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PERLOWAGORA-SZUMLEWICZ, A. Schistosoma mansoni: Humoral Transfer of Protective Factors produced by Irradiated Cercariæ. Nature 204, 1009–1010 (1964). https://doi.org/10.1038/2041009a0

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  • DOI: https://doi.org/10.1038/2041009a0

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