Abstract
WE previously reported1 changes of the absorption spectrum of nicotinamide adenine dinucleotide (coenzyme I, abbreviated NAD+) in solutions containing orthophosphate. In an extension of those investigations2, it has been observed that dihydronicotinamide-adenine dinucleotide (reduced coenzyme I, abbreviated NADH) also reacts with orthophosphate, but in an entirely different manner. Similar changes were observed with dihydronicotinamide adenine dinucleotide phosphate (reduced coenzyme II, abbreviated NADPH) and certain other NADH-analogues. This is a preliminary report of our findings3.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Ungar, F., and Alivisatos, S. G. A., Biochim. Biophys. Acta, 46, 406 (1961).
Ungar, F., Abraham, G., and Alivisatos, S. G. A. (in preparation).
Alivisatos, S. G. A., Ungar, F., and Abraham, G. (submitted for publication).
Frost, A. A., and Pearson, R. G., Kinetics and Mechanism, second ed., 166 (John Wiley and Sons, New York, 1961).
Anderson, jun., A. G., and Berkelhammer, G., J. Amer. Chem. Soc., 80, 992 (1958).
Kosower, E. M., Molecular Biochemistry, 209 (McGraw-Hill, New York, 1962).
Wallenfels, K., Hofmann, D., and Schüly, H., Liebig's Ann. Chem., 621, 188 (1959).
Weber, G., Nature, 180, 1409 (1957); J. chim. phys., 55, 878 (1958).
Chaykin, S., Meinhart, J. O., and Krebs, E. G., J. Biol. Chem., 220, 811 (1956).
Griffiths, D. E., Fed. Proc., 22, 1064 (1963).
Brierley, G., Murer, E., Bachmann, E., and Green, D. E., J. Biol. Chem. 238, 3482 (1963).
Herskovits, T. T., and Laskowski, jun., M., J. Biol. Chem., 237, 2481 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ALIVISATOS, S., UNGAR, F. & ABRAHAM, G. Non-enzymatic Interactions of Reduced Coenzyme I with Inorganic Phosphate and Certain Other Anions. Nature 203, 973–975 (1964). https://doi.org/10.1038/203973a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/203973a0
This article is cited by
-
Influence of electrode potential, pH and NAD+ concentration on the electrochemical NADH regeneration
Scientific Reports (2022)
-
Role of inorganic phosphate during electron transfer in the redox system NADH+flavin
Journal of Applied Spectroscopy (2006)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
