Abstract
IN their recent extensive investigation of the reversible reaction of deoxyribonucleic acid (DNA) and bivalent mercuric compounds1, Yamane and Davidson2 introduced a useful new kind of pH-stat titration which they applied both to their investigation of the DNA–HgII interactions and to the examination of DNA–Ag+ interactions3.
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References
Katz, S., J. Amer. Chem. Soc., 74, 2238 (1952).
Yamane, T., and Davidson, N., J. Amer. Chem. Soc., 83, 2599 (1961).
Yamane, T., and Davidson, N., Biochim. Biophys. Acta, 55, 609 (1962).
Thomas, C., J. Amer. Chem. Soc., 76, 6032 (1954).
Katz, S., Nature, 194, 569 (1962).
Katz, S., Biochim. Biophys. Acta, 68, 240 (1963).
cf., for example, Klotz, I., in The Proteins, edit. by Neurath, H., and Bailey, K., 1, Part B, 790 (Academic Press, New York, 1953).
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KATZ, S. Theory of the pH-stat Titration of a Polyfunctional Reactant by a Competitive ‘Ligandee’. Nature 203, 858–859 (1964). https://doi.org/10.1038/203858a0
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DOI: https://doi.org/10.1038/203858a0
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